Computerized calculation of biological potency: presentation of the interactive computer program "POTENCY" (assays: "2 + 2" doses, "3 + 3" doses, "twin cross-over assay" and "probit analysis" ("2 + 2" doses).

M B Arambasić

PubMed · 11822234

Computerized calculation of biological potency: presentation of the interactive computer program "POTENCY" (assays: "2 + 2" doses, "3 + 3" doses, "twin cross-over assay" and "probit analysis" ("2 + 2" doses).

Abstract

Paper presents the interactive computer program "POTENCY" written in BASIC program language, based on the algorithm for classifying biological assays using the assays: "2 + 2" doses, "3 + 3" doses, twin cross-over assay and probit analysis ("2 + 2" doses) described in Yugoslav Pharmacopeia (Ph. Jug. IV). The program execution is presented by assay examples of biological potency calculation described in European Pharmacopeia (Eur. Ph. 1997). The assay-examples have simultaneously been the measure of program execution correctness.

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M B Arambasić. Computerized calculation of biological potency: presentation of the interactive computer program "POTENCY" (assays: "2 + 2" doses, "3 + 3" doses, "twin cross-over assay" and "probit analysis" ("2 + 2" doses).. https://pubmed.ncbi.nlm.nih.gov/11822234/

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