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Lab-on-a-chip: applications in proteomics.

Stephane Mouradian
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Abstract

Recent advances in chip-based separation of proteins provide methods that are faster and more convenient than conventional gel electrophoresis. Rapid and automated protein sizing on a chip is at the commercial stage and first attempts have been made to perform two-dimensional separation on a chip. Numerous designs have been described to interface a microfluidic chip to a mass spectrometer. Impressive integration efforts are demonstrated by the ability to perform on-chip trypsin digestion, separation and injection into a mass spectrometer with a single device.

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AnimalsElectrophoresis, Gel, Two-DimensionalFluorescent DyesHumansMicrochemistryMiniaturizationProteinsProteomeJournal ArticleReview

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Stephane Mouradian. 2002. Lab-on-a-chip: applications in proteomics.. https://doi.org/10.1016/s1367-5931(01)00280-0

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