Deafness-induced changes in the auditory pathway: implications for cochlear implants.

R K Shepherd; N A Hardie

doi:10.1159/000046843

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PubMed · 11847461

Deafness-induced changes in the auditory pathway: implications for cochlear implants.

R K Shepherd·N A Hardie

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Abstract

A profound sensorineural hearing loss induces significant pathological and atrophic changes within the cochlea and central auditory pathway. We describe these deafness-induced morphological and functional changes following controlled lesions of the cochlea in experimental animals. Such changes are generally consistent with the limited number of reports describing deafness-induced changes observed in human material. The implications of these pathophysiological changes within the auditory pathway on cochlear implant function are discussed. Finally, the plastic response of the deafened auditory system to electrical stimulation of the auditory nerve is reviewed in light of the clinical implications for cochlear implant recipients.

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Animals Auditory Pathways Cats Cochlear Implantation Cochlear Nucleus Deafness Evoked Potentials, Auditory, Brain Stem Mesencephalon Organ of Corti Spiral Ganglion Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.Review

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R K Shepherd, N A Hardie. Deafness-induced changes in the auditory pathway: implications for cochlear implants.. https://doi.org/10.1159/000046843

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