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Direct interactions between rab GTPases and cargo.

Elizabeth Smythe
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Abstract

The rab family of small GTPases has numerous roles in intracellular transport including budding, tethering, and fusion of vesicles as well as organelle motility. New data show that cargo proteins are also rab effectors and can therefore regulate their own trafficking by direct interactions with the transport machinery.

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AnimalsCell PolarityEndocytosisHumansImmunoglobulin A, SecretoryIntestinal MucosaMacromolecular SubstancesProtein TransportReceptor, Angiotensin, Type 1Receptors, AngiotensinReceptors, Polymeric Immunoglobulinrab GTP-Binding Proteinsrab3 GTP-Binding Proteinsrab5 GTP-Binding ProteinsJournal ArticleReview

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Elizabeth Smythe. 2002. Direct interactions between rab GTPases and cargo.. https://doi.org/10.1016/s1097-2765(02)00462-8

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