Haptoglobin and malaria.

N H Hunt; C Driussi; L Sai-Kiang

doi:10.1179/135100001101536508

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PubMed · 11865983

Haptoglobin and malaria.

N H Hunt·C Driussi·L Sai-Kiang

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Abstract

Haptoglobin gene knockout mice and wild-type controls were infected with Plasmodium berghei ANKA or Plasmodium chabaudi. The peak parasitaemia and parasite burden were higher in Hp-/- mice than in Hp+/+ mice. The increase in spleen weight following malaria infection was smaller in Hp-/- mice than in Hp+/+ animals. The occurrence of cerebral malaria in P. berghei ANKA infection was not different in Hp gene knockout mice and their controls.

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Animals Female Haptoglobins Malaria Male Mice Mice, Inbred C57BL Mice, Inbred CBA Mice, Knockout Organ Size Plasmodium berghei Sex Factors Spleen Journal Article Research Support, Non-U.S. Gov't

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N H Hunt, C Driussi, L Sai-Kiang. 2001. Haptoglobin and malaria.. https://doi.org/10.1179/135100001101536508

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