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Coding rules for amino acids in the genetic code: the genetic code is a minimal code of mutational deterioration.

Liaofu Luo·Xiaoqin Li
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Abstract

Coding rules for amino acids in the genetic code are discussed from the point that the genetic code is a minimal code of mutational deterioration. The global mutational deterioration (GMD) function is defined through several parameters describing single base mutations and amino acid distances. The problem of searching for the global minimum of the GMD function is discussed in some detail. From GMD minimization under initial constraints we have succeeded in deducing the standard genetic code.

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Amino AcidsGenetic CodeModels, GeneticMutationJournal ArticleResearch Support, Non-U.S. Gov't

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Liaofu Luo, Xiaoqin Li. 2002. Coding rules for amino acids in the genetic code: the genetic code is a minimal code of mutational deterioration.. https://doi.org/10.1023/a%3A1013963505140

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