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Understanding atherosclerosis through mouse genetics.

Sonal S Sheth·Andres Deluna·Hooman Allayee·Aldons J Lusis
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Abstract

During the past year studies with mouse models have significantly clarified our understanding of atherosclerosis. Noteworthy achievements include: the discovery of a number of novel genes and pathways; new evidence emphasizing the role of lymphocytes in atherogenesis; the development of mouse models exhibiting advanced lesions with evidence of thrombosis; and new results indicating an anti-atherogenic effect of testosterone.

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AnimalsArteriosclerosisDisease Models, AnimalHumansLipoproteinsMiceMolecular BiologyJournal ArticleReview

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Sonal S Sheth, Andres Deluna, Hooman Allayee, Aldons J Lusis. 2002. Understanding atherosclerosis through mouse genetics.. https://doi.org/10.1097/00041433-200204000-00010

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