Molecular dynamics simulations.

Tomas Hansson; Chris Oostenbrink; WilfredF van Gunsteren

doi:10.1016/s0959-440x(02)00308-1

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PubMed · 11959496

Molecular dynamics simulations.

Tomas Hansson·Chris Oostenbrink·WilfredF van Gunsteren

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Abstract

Molecular dynamics simulations have become a standard tool for the investigation of biomolecules. Simulations are performed of ever bigger systems using more realistic boundary conditions and better sampling due to longer sampling times. Recently, realistic simulations of systems as complex as transmembrane channels have become feasible. Simulations aid our understanding of biochemical processes and give a dynamic dimension to structural data; for example, the transformation of harmless prion protein into the disease-causing agent has been modeled.

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Tomas Hansson, Chris Oostenbrink, WilfredF van Gunsteren. 2002. Molecular dynamics simulations.. https://doi.org/10.1016/s0959-440x(02)00308-1

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