Human immunodeficiency virus (HIV) Type 1 reverse transcriptase resistance mutations in hepatitis B virus (HBV)-HIV-coinfected patients treated for HBV chronic infection once daily with 10 milligrams of adefovir dipivoxil combined with lamivudine.

Constance Delaugerre; Anne-Geneviève Marcelin; Vincent Thibault; Gilles Peytavin; Tony Bombled; Marie-Valérie Bochet; Christine Katlama; Yves Benhamou; Vincent Calvez

doi:10.1128/aac.46.5.1586-1588.2002

PubMed · 11959607

Human immunodeficiency virus (HIV) Type 1 reverse transcriptase resistance mutations in hepatitis B virus (HBV)-HIV-coinfected patients treated for HBV chronic infection once daily with 10 milligrams of adefovir dipivoxil combined with lamivudine.

Constance Delaugerre·Anne-Geneviève Marcelin·Vincent Thibault·Gilles Peytavin·Tony Bombled·Marie-Valérie Bochet·Christine Katlama·Yves Benhamou·Vincent Calvez

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Abstract

Adefovir dipivoxil (ADV) at a suboptimal concentration for human immunodeficiency virus type 1 (HIV-1) (10 mg once daily) can be used to treat hepatitis B virus (HBV) infection in HIV-1-HBV-coinfected patients and does not, even in the case of uncontrolled HIV-1 replication, select for either ADV mutations at codons 65 and 70 or any other particular HIV-1 reverse transcriptase resistance profile.

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Adenine Antiviral Agents Drug Resistance, Viral Drug Therapy, Combination HIV Infections HIV Reverse Transcriptase HIV-1 Hepatitis B virus Hepatitis B, Chronic Humans Lamivudine Mutation Organophosphonates Reverse Transcriptase Inhibitors Journal Article

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Constance Delaugerre, Anne-Geneviève Marcelin, Vincent Thibault, Gilles Peytavin, Tony Bombled, Marie-Valérie Bochet, Christine Katlama, Yves Benhamou, Vincent Calvez. 2002. Human immunodeficiency virus (HIV) Type 1 reverse transcriptase resistance mutations in hepatitis B virus (HBV)-HIV-coinfected patients treated for HBV chronic infection once daily with 10 milligrams of adefovir dipivoxil combined with lamivudine.. https://doi.org/10.1128/aac.46.5.1586-1588.2002

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