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FIP: a highly automated beamline for multiwavelength anomalous diffraction experiments.

M Roth·P Carpentier·O Kaïkati·J Joly·P Charrault·M Pirocchi·R Kahn·E Fanchon·L Jacquamet·F Borel·A Bertoni·P Israel-Gouy·J L Ferrer
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Abstract

FIP is a French Collaborating Research Group (CRG) beamline at the European Synchrotron Radiation Facility (ESRF) dedicated exclusively to crystallography of biological macromolecules, with a special emphasis on multiwavelength anomalous diffraction data collection in the 0.7-1.81 A wavelength range. The optics, consisting of long cylindrical grazing-angle mirrors associated with a cryocooled double-crystal monochromator, delivers an optimal beam in the corresponding energy range. The high level of automation, which includes automated crystal centring, automated data-collection management and data processing, makes the use of this beamline very easy. This is illustrated by the large number of challenging structures that have been solved since 1999.

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AutomationCalibrationCrystallographyElectronicsFranceFreezingHumansNADP TranshydrogenasesNuclear Cap-Binding Protein ComplexProtein ConformationProteinsReceptors, Granulocyte-Macrophage Colony-Stimulating FactorReceptors, InterleukinSoftwareSpectrometry, FluorescenceSynchrotronsTemperatureX-Ray DiffractionJournal ArticleResearch Support, Non-U.S. Gov't

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M Roth, P Carpentier, O Kaïkati, J Joly, P Charrault, M Pirocchi, R Kahn, E Fanchon, L Jacquamet, F Borel, A Bertoni, P Israel-Gouy, J L Ferrer. 2002-04-26. FIP: a highly automated beamline for multiwavelength anomalous diffraction experiments.. https://doi.org/10.1107/s0907444902003943

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