PubMed · 11982253
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K Devine. Curing & caring.. https://doi.org/10.1111/j.1552-6356.2001.tb01271.x
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Establishing the existence of a genetic contribution to disease is the first step in identifying the underlying gene defect(s). This can present a considerable challenge, particularly in diseases where the genetic contribution is complex in nature. Clinically well-characterized cohorts and large inter-institutional collaborations will be required to identify genes involved in complex disease.
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