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WNT signaling and lymphocyte development.

Marc van de Wetering·Wim de Lau·Hans Clevers
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Abstract

Developmental studies in model organisms have revealed that cell fate decisions are governed by only a handful of highly conserved signal transduction cascades. Recent data indicate that at least two of these, the Wnt and the Notch cascades, have been recruited by the vertebrate immune system to control early lymphopoiesis.

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AnimalsCell DifferentiationCell LineageDNA-Binding ProteinsHumansLymphocytesLymphoid Enhancer-Binding Factor 1MiceMice, KnockoutProto-Oncogene ProteinsSignal TransductionThymus GlandTranscription FactorsWnt ProteinsZebrafish ProteinsJournal ArticleReview

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Marc van de Wetering, Wim de Lau, Hans Clevers. 2002. WNT signaling and lymphocyte development.. https://doi.org/10.1016/s0092-8674(02)00709-2

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