Exercise enhances and protects brain function.

Carl W Cotman; Christie Engesser-Cesar

doi:10.1097/00003677-200204000-00006

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Exercise enhances and protects brain function.

Carl W Cotman·Christie Engesser-Cesar

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Abstract

Physical activity, in the form of voluntary wheel running, induces gene expression changes in the brain. Animals that exercise show an increase in brain-derived neurotrophic factor, a molecule that increases neuronal survival, enhances learning, and protects against cognitive decline. Microarray analysis of gene expression provides further support that exercise enhances and supports brain function.

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Animals Brain Brain-Derived Neurotrophic Factor Estrogens Oligonucleotide Array Sequence Analysis Physical Conditioning, Animal Physical Exertion Synapses Up-Regulation Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.Review

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Carl W Cotman, Christie Engesser-Cesar. 2002. Exercise enhances and protects brain function.. https://doi.org/10.1097/00003677-200204000-00006

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