Calcium quarks.

Ernst Niggli; Marcel Egger

doi:10.2741/a840

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PubMed · 11991844

Calcium quarks.

Ernst Niggli·Marcel Egger

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Abstract

Elementary subcellular Ca2+ signals arising from the opening of single ion channels may offer the possibility to examine the stochastic behavior and the microscopic chemical reaction rates of these channel proteins in their natural environment. Such an analysis can yield detailed information about the molecular function that cannot be derived from recordings obtained from an ensemble of channels. In this review, we summarize experimental evidence suggesting that Ca2+ sparks, elementary Ca2+ signaling events of cardiac and skeletal muscle excitation contraction coupling, may be comprised of a number of smaller Ca2+ signaling events, the Ca2+ quarks.

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Animals Calcium Calcium Signaling Muscle, Skeletal Photolysis Ryanodine Receptor Calcium Release Channel Sarcoplasmic Reticulum Sodium-Calcium Exchanger Ultraviolet Rays Journal Article Research Support, Non-U.S. Gov't Review

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Ernst Niggli, Marcel Egger. 2002-05-01. Calcium quarks.. https://doi.org/10.2741/a840

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