PubMed · 12024306
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Mary K. Boudreaux. 2001. Platelets past, present, and future.. https://doi.org/10.1111/j.1939-165x.2001.tb00415.x
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Precision oncology relies on integrating tumour fraction, variant allele frequency, clonal haematopoiesis of indeterminate potential assessment, pathogenicity, and clinical context into next-generation sequencing interpretation, enabling biologically informed and clinically meaningful treatment decisions while reducing the risk of overinterpreting nontumour or nonactionable genomic alterations.