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PubMed · 12047936

Antisense RNAs everywhere?

E Gerhart H Wagner·Klas Flärdh
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Abstract

In recent years, systematic searches of both prokaryote and eukaryote genomes have identified a staggering number of small RNAs, the biological functions of which remain unknown. Small RNA-based regulators are well known from bacterial plasmids. They act on target RNAs by sequence complementarity; that is, they are antisense RNAs. Recent findings suggest that many of the novel orphan RNAs encoded by bacterial and eukaryotic chromosomes might also belong to a ubiquitous, heterogeneous class of antisense regulators of gene expression.

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Base SequenceChromosomes, BacterialGene Expression RegulationMolecular Sequence DataNucleic Acid ConformationRNA, AntisenseNewsResearch Support, Non-U.S. Gov't

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E Gerhart H Wagner, Klas Flärdh. 2002. Antisense RNAs everywhere?. https://doi.org/10.1016/s0168-9525(02)02658-6

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