Targeting fragile X.

Ilse Gantois; R Frank Kooy

doi:10.1186/gb-2002-3-5-reviews1014

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PubMed · 12049671

Targeting fragile X.

Ilse Gantois·R Frank Kooy

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Abstract

Ten years after the identification of the gene responsible for fragile X syndrome, recent studies have revealed a list of mRNAs bound by the fragile X gene product and have identified specific sequences required for the interaction between the fragile X protein and its targets. These results are a breakthrough in understanding why absence of the fragile X protein leads to mental retardation.

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Animals Binding Sites Fragile X Messenger Ribonucleoprotein 1 Fragile X Syndrome Humans Intellectual Disability Multigene Family Nerve Tissue Proteins Nucleic Acid Conformation RNA RNA, Messenger RNA-Binding Proteins Journal Article Research Support, Non-U.S. Gov't Review

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Ilse Gantois, R Frank Kooy. 2002-04-25. Targeting fragile X.. https://doi.org/10.1186/gb-2002-3-5-reviews1014

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