Submillimeter-wave phonon modes in DNA macromolecules.

D L Woolard; T R Globus; B L Gelmont; M Bykhovskaia; A C Samuels; D Cookmeyer; J L Hesler; T W Crowe; J O Jensen; J L Jensen; W R Loerop

doi:10.1103/physreve.65.051903

PubMed · 12059589

Submillimeter-wave phonon modes in DNA macromolecules.

D L Woolard·T R Globus·B L Gelmont·M Bykhovskaia·A C Samuels·D Cookmeyer·J L Hesler·T W Crowe·J O Jensen·J L Jensen·W R Loerop

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Abstract

A detailed investigation of phonon modes in DNA macromolecules is presented. This work presents experimental evidence to confirm the presence of multiple dielectric resonances in the submillimeter-wave spectra (i.e., approximately 0.01-10 THz) obtained from DNA samples. These long-wave (i.e., approximately 1-30 cm(-1)) absorption features are shown to be intrinsic properties of the particular DNA sequence under study. Most importantly, a direct comparison of spectra between different DNA samples reveals a large number of modes and a reasonable level of sequence-specific uniqueness. This work establishes the initial foundation for the future use of submillimeter-wave spectroscopy in the identification and characterization of DNA macromolecules.

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Biophysics DNA Models, Theoretical Nucleic Acid Conformation Spectrum Analysis Journal Article Research Support, U.S. Gov't, Non-P.H.S.

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D L Woolard, T R Globus, B L Gelmont, M Bykhovskaia, A C Samuels, D Cookmeyer, J L Hesler, T W Crowe, J O Jensen, J L Jensen, W R Loerop. 2002-05-03. Submillimeter-wave phonon modes in DNA macromolecules.. https://doi.org/10.1103/physreve.65.051903

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