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Antimicrobial diterpenoids from Eupatorium glutinosum (Asteraceae).

H R El-Seedi·T Ohara·N Sata·S Nishiyama
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Abstract

The antimicrobial properties of the hexane extract from the leaves and twigs of the Eupatorium glutinosum was tested against two Gram-negative and two Gram-positive bacteria. Bioassay guided fractionation leads characteristically to isolation and structure elucidation of two active compounds: 15-hydroxy-7-labden-17-oic acid and its acetate. These results validate the vernacular medicinal uses of the plant in folkloric medicine. Dammara-20, 24-dien-3-acetate, stigmasterol and epi-friedelanone have been also isolated in addition to the palmitate of nepehinol for the first time as naturally occurring.

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Anti-Bacterial AgentsDiterpenesEupatoriumMicrobial Sensitivity TestsPlant BarkPlant ExtractsPlant LeavesJournal ArticleResearch Support, Non-U.S. Gov't

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H R El-Seedi, T Ohara, N Sata, S Nishiyama. 2002. Antimicrobial diterpenoids from Eupatorium glutinosum (Asteraceae).. https://doi.org/10.1016/s0378-8741(02)00101-0

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