PubMed · 12080858
[Development of biodegradable polymer scaffolds for bone tissue engineering].
Abstract
OBJECTIVE: To investigate the selection and manufacture of ideal extracellular matrix materials in bone tissue engineering. METHODS: The recent literatures about biodegradable polymers served as culture scaffolds of osteoblasts were widely reviewed, the advantages and disadvantages of biodegradable synthetic polymers and natural polymers were analysed. RESULTS: The ideal extracellular matrix material in bone tissue engineering should be made up of inorganic materials, synthetic polymers and natural polymers, which possesses morphological structure of three-dimensional foam with self-mediated drug slow delivery system of bone growth factors. CONCLUSION: The design and manufacture of combined extracellular matrix materials in bone tissue engineering is a very important and urgent challenge.
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L Zheng, Q Wang, G X Pei. 2000. [Development of biodegradable polymer scaffolds for bone tissue engineering].. https://pubmed.ncbi.nlm.nih.gov/12080858/
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