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PubMed · 12086738

Competing on the edge.

Massimo Scanziani
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Abstract

Fast-acting neurotransmitters can exit the synaptic cleft and bind to extrasynaptic receptors. This process is modulated by transmitter uptake mechanisms (transporters). A new study focusing on glutamate-mediated transmission in the cerebellum describes the specific role of neuronal transporters in modulating the access of glutamate to extrasynaptic metabotropic glutamate receptors, and reveals important consequences of extrasynaptic signaling on synaptic plasticity.

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Amino Acid Transport System X-AGAnimalsCerebellumGlutamic AcidNeuronal PlasticityReceptors, Metabotropic GlutamateSynaptic TransmissionJournal ArticleReview

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Massimo Scanziani. 2002. Competing on the edge.. https://doi.org/10.1016/s0166-2236(02)02155-0

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PubMed2007

Alterations of amino acids and glutamate transport in the DBA/2J mouse retina; possible clues to degeneration.

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