Cell lineage specification in the nervous system.

Gundula Edenfeld; Jan Pielage; Christian Klämbt

doi:10.1016/s0959-437x(02)00328-3

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Cell lineage specification in the nervous system.

Gundula Edenfeld·Jan Pielage·Christian Klämbt

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Abstract

Nervous system development requires the specification of numerous neural stem cells. Subsequently these stem cells divide in a spatially and temporally controlled manner to generate the diverse cell types found in the different layers of the nervous system. Lineage specification is brought about by transcriptional regulators, which often act as transcriptional repressors.

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Animals Cell Differentiation Drosophila Gene Expression Regulation, Developmental Mice Nervous System Stem Cells Transcription Factors Transcription, Genetic Journal Article Review

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Gundula Edenfeld, Jan Pielage, Christian Klämbt. 2002. Cell lineage specification in the nervous system.. https://doi.org/10.1016/s0959-437x(02)00328-3

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