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PubMed · 12121639

Genetic code: introducing pyrrolysine.

Michael Ibba·Dieter Söll
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Abstract

Monomethylamine methyltransferase of the archaebacterium Methanosarcina barkeri contains a novel amino acid, pyrrolysine, encoded by the termination codon UAG. Initial studies suggest that pyrrolysine may be co-translationally inserted during protein synthesis, probably by a mechanism analogous to that operating during selenocysteine incorporation.

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Amino Acyl-tRNA SynthetasesArchaeal ProteinsCodonGenes, ArchaealLysineMethanosarcina barkeriMethyltransferasesProtein BiosynthesisJournal ArticleReview

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Michael Ibba, Dieter Söll. 2002-07-09. Genetic code: introducing pyrrolysine.. https://doi.org/10.1016/s0960-9822(02)00947-8

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