PubMed Health⌕ Search
Home/Archive/PubMed

PubMed · 12139386

Challenges in paediatric perfusion.

W J Brawn
View original source ↗Export metadata ↓

Abstract

In the last 50 years cardiopulmonary bypass has evolved dramatically, so that even the most complex heart lesions can be repaired successfully. However, we are aware that whilst survival may be excellent, organ damage, even though minor, particularly to the central nervous system is common. The next challenge in paediatric perfusion is to reduce this damage to a minimum.

Explore related subjects

Brain Damage, ChronicCardiopulmonary BypassChildHumansPerfusionJournal ArticleReview

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

W J Brawn. 2002. Challenges in paediatric perfusion.. https://doi.org/10.1191/0267659102pf589oa

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed2006

Neurocognitive consequences of surgically corrected congenital heart defects: A review.

With advances in surgical procedures, neuropsychological assessment after congenital heart defects and pre, peri- and/or postoperative predictors of adverse outcome has become an important focus in research. We aim to summarize neuropsychological sequelae associated with different types of congenital heart defects, critically review the methodology used in more than 20 empirical studies that were retrieved from biomedical electronic search engines, and identify possible directions for future research. Despite the lack of adequate control groups and long-term studies, there seem to be some cognitive deficits. The largest group of children with isolated congenital heart defects present with normal intellectual capacities. However, they tend to show language deficits and motor dysfunction. Although performances on memory tasks are good, unambiguous conclusions concerning their attentional and executive functioning are still lacking. Serious behavioral problems are not an issue. In addition to a detailed description of the (neuro) psychological consequences of pediatric cardiac surgery, an overview of the predictors of the cognitive defects is provided.

Brain Damage, Chronic↗