Systemic inflammatory response syndrome.

C A Botwinski

doi:10.1891/0730-0832.20.5.21

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Systemic inflammatory response syndrome.

C A Botwinski

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Abstract

Despite advances in perinatal care in the past decade, sepsis and its complications continue to present problems for the neonate, remaining a major cause of neonatal morbidity and mortality. Sepsis research is focusing on how the neonate (host) responds to bacteria. The newborn may develop a systemic reaction to bacteria that induces the release of substances known as inflammatory mediators. Termed the systemic inflammatory response syndrome (SIRS), this reaction is believed to be responsible for the signs and symptoms of sepsis. This article introduces the neonatal nurse to SIRS, providing an overview of various inflammatory mediators and cytokines, their clinical consequences, and potential new therapies in the management of SIRS.

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Blood Coagulation Disease Progression Humans Infant, Newborn Inflammation Inflammation Mediators Intensive Care, Neonatal Neonatal Nursing Risk Factors Systemic Inflammatory Response Syndrome Journal Article Review

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C A Botwinski. 2001. Systemic inflammatory response syndrome.. https://doi.org/10.1891/0730-0832.20.5.21

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