A new trigger for T cells.

Mark M Davis

doi:10.1016/s0092-8674(02)00865-6

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A new trigger for T cells.

Mark M Davis

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Abstract

Understanding the early events in T cell activation and signaling is an active area of research. A recent study has described a new trigger for T cell activation, involving a TCR-ligand-induced conformational change in CD3epsilon that permits binding of the adaptor protein Nck.

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Adaptor Proteins, Signal Transducing Animals CD3 Complex Cell Membrane Humans Immune System Lymphocyte Activation Oncogene Proteins Protein Binding Receptors, Antigen, T-Cell T-Lymphocytes Journal Article Review

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Mark M Davis. 2002-08-09. A new trigger for T cells.. https://doi.org/10.1016/s0092-8674(02)00865-6

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