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PubMed · 12231352

T-cell activation: a multidimensional signaling network.

Su-Yi Tseng·Michael L Dustin
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Abstract

Naïve T cell activation requires the interactions of antigen receptors, adhesion molecules and co-stimulatory molecules. Antigen receptors and adhesion molecules are involved in spatio-temporal movement to form a stable immunological synapse. This stable junction interrupts T cell migration, and provides a platform for temporally regulated co-stimulatory receptor signaling spanning a period of days.

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AnimalsCell AdhesionCell DifferentiationCell DivisionCell MovementHumansLymph NodesLymphocyte ActivationSignal TransductionSynapsesT-LymphocytesTime FactorsJournal ArticleReview

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Su-Yi Tseng, Michael L Dustin. 2002. T-cell activation: a multidimensional signaling network.. https://doi.org/10.1016/s0955-0674(02)00370-8

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