Antigen-induced changes in lymphocyte circulatory patterns.

S J Black

doi:10.1002/eji.1830050304

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Antigen-induced changes in lymphocyte circulatory patterns.

S J Black

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Abstract

The effect of a splenic or lymph node anti-sheep red blood cell response on lymphocyte migration patterns in mice was studied. It was found that trapping of lymphocytes in these stimulated organs was indiscriminate and was followed by a period of restricted cell entry or localization; furthermore, reduced cell localization in the spleen, during the splenic response, was accompanied by a reduction in the number of cells localizing in unstimulated brachial and axillary lymph nodes. These results were taken to indicate that major changes occur in lymphocyte circulation during strong splenic immune responses.

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Animals Antibody Formation Antigens Cell Movement Cyclophosphamide Erythrocytes Female Immunologic Memory Injections, Subcutaneous Lymph Nodes Lymphocyte Activation Lymphocytes Male Mice Mice, Inbred Strains Spleen Journal Article

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S J Black. 1975. Antigen-induced changes in lymphocyte circulatory patterns.. https://doi.org/10.1002/eji.1830050304

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