PubMed · 123433
Acne detergicans.
Abstract
Popular brands of soaps and shampoos were assayed for comedogenicity in the rabbit ear. Only a small number produced hyperkeratosis when applied at a 25% concentration. Bacteriostatic substances, especially hexachlorophene, were mildly comedogenic. Conventional soaps include salts of fatty acids; the latter are known comedogens. The obsessive use of soaps by patients with acne vulgaris may aggravate the disease and result in its extension to unusual locations.
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O H Mills, A M Klingman. 1975. Acne detergicans.. https://pubmed.ncbi.nlm.nih.gov/123433/
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