Compensatory fluid administration for preoperative dehydration--does it improve outcome?

K Holte; H Kehlet

doi:10.1034/j.1399-6576.2002.460906.x

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Compensatory fluid administration for preoperative dehydration--does it improve outcome?

K Holte·H Kehlet

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Abstract

BACKGROUND: Preoperative fasting may lead to a fluid deficit of about 1 litre, which may contribute to perioperative discomfort and morbidity. We therefore examined the association between perioperatively administered fluids aiming to correct dehydration and clinical outcome. METHODS: Review of randomized, controlled, clinical trials evaluating clinical outcome, in which fluid versus no fluid was administered pre- or intraoperatively, attempting to correct preoperative fluid deficits. Data were obtained from a Medline search (1966-2001), and references cited in original papers. Seventeen trials met the inclusion criteria. RESULTS: Based on the amount of fluid administered, we divided the studies into two groups. In nine studies, fluid administration was <1 litre, and in eight studies > or =1 litre of fluid was administered. Administration of low-dose fluid reduced preoperative thirst, but the limited data do not allow conclusions on postoperative outcome such as nausea, vomiting, headache and pain. Administration of > or =1 litre fluid generally reduced postoperative drowsiness and dizziness, while the effects on postoperative nausea, vomiting and thirst has not been clarified. CONCLUSION: Fluid administration to compensate preoperative dehydration improves symptoms related to dehydration. Based on the available data, administration of about 1 litre fluid pre- or intraoperatively in patients having fasted for minor surgical procedures seems rational.

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Dehydration Fluid Therapy Humans Outcome Assessment, Health Care Perioperative Care Postoperative Complications Randomized Controlled Trials as Topic Journal Article Meta-Analysis

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K Holte, H Kehlet. 2002. Compensatory fluid administration for preoperative dehydration--does it improve outcome?. https://doi.org/10.1034/j.1399-6576.2002.460906.x

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