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PubMed · 12377565

Structural proteomics: the potential of high-throughput structure determination.

Molly B Schmid
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Abstract

The pharmaceutical industry has embraced genomics as a means to identify new biological targets for target-based drug discovery approaches. Now, genomics is driving a substantial effort in protein structure determination and structure prediction. These structures will provide the opportunity to undertake structure-guided drug discovery programs in the search for new classes of broad-spectrum antibiotics. In addition, these structures could provide structure-based criteria to prioritize certain targets for focused drug discovery programs.

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Anti-Bacterial AgentsAnti-Infective AgentsCrystallographyDrug DesignGenomicsImaging, Three-DimensionalMolecular StructurePeptide MappingProtein ConformationProteomicsTechnology, PharmaceuticalJournal ArticleReview

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BibTeXRIS

Molly B Schmid. 2002. Structural proteomics: the potential of high-throughput structure determination.. https://doi.org/10.1016/s0966-842x(02)02443-5

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