Complement in allergy and asthma.

Norma P Gerard; Craig Gerard

doi:10.1016/s0952-7915(02)00410-7

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Complement in allergy and asthma.

Norma P Gerard·Craig Gerard

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Abstract

The complement system is a vital link between innate and adaptive immunity. Recently, several investigators have implicated the complement anaphylatoxins C3a and C5a as potential effectors in Type 1 hypersensitivity reactions, including urticaria, rhinitis and asthma. Thus, complement activation may synergize with classical IgE mediated responses, and inhibition of complement may prove therapeutic.

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Anaphylatoxins Animals Antigens, CD Asthma Complement Activation Complement System Proteins Hypersensitivity Mice Receptor, Anaphylatoxin C5a Receptors, Complement Sepsis Journal Article Review

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Norma P Gerard, Craig Gerard. 2002. Complement in allergy and asthma.. https://doi.org/10.1016/s0952-7915(02)00410-7

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