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Wnt signaling: a complex issue.

Bart Hendriks·Ernst Reichmann
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Abstract

The development of tissues and organs in multicellular organisms is controlled by the interplay of several signaling pathways that cross-talk to provide positional information and induce cell fate specification. Together with other families of secreted factors such as TGF beta s, FGFs, Hedgehog and Notch proteins, Wnt growth factors are crucially implicated in these processes. Here, we will first discuss molecular mechanisms and then consider some biological consequences of Wnt signaling.

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AnimalsCytoskeletal ProteinsGrowth SubstancesHumansNeoplasmsProto-Oncogene ProteinsReceptors, Growth FactorSignal TransductionTranscription FactorsWnt ProteinsZebrafish ProteinsJournal ArticleResearch Support, Non-U.S. Gov'tReview

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Bart Hendriks, Ernst Reichmann. 2002. Wnt signaling: a complex issue.. https://doi.org/10.4067/s0716-97602002000200019

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