PubMed Health⌕ Search
Home/Archive/PubMed

PubMed · 12422772

[Sprue].

H Schwacha
View original source ↗Export metadata ↓

Abstract

Coeliac disease is an inflammatory disease of the small intestine. Coeliac disease occurs in individuals suffering from a genetically caused gluten intolerance. Mean clinical findings are malabsorption for several nutrients or steatorrhoe. Silent or latent courses are common. The diagnosis is based upon the histological finding of villous atrophy in duodenal or jejunal biopsies. Anti-endomysium-antibodies are of high sensitivity and specificity. After gluten free diet the coeliac disease improves. Gluten free diet has to be taken lifelong preventing complications i.e. osteoporosis and malignancies.

Explore related subjects

BiopsyCeliac DiseaseGenetic TestingGlutensHumansIntestinal MucosaEnglish AbstractJournal Article

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

H Schwacha. 2002-10-09. [Sprue].. https://doi.org/10.1024/0369-8394.91.41.1687

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed2003

Diagnostic hysteroscopy: a valuable diagnostic tool in the diagnosis of structural intra-cavital pathology and endometrial hyperplasia or carcinoma?. Six years of experience with non-clinical diagnostic hysteroscopy.

OBJECTIVE: 1045 diagnostic hysteroscopic procedures performed throughout six consecutive years were evaluated, focussing on its value in diagnosing endometrial hyperplasia and carcinoma. DESIGN: Retrospective study performed in the gynaecological endoscopy clinic of a training hospital. Subjects were 1045 pre- and post-menopausal patients. RESULTS: A normal cavity was found in 54.2%. Most common abnormal findings were fibroids (21.0%) and endometrial polyps (14.4%). Hysteroscopically diagnosed hyperplasia of the endometrium was confirmed histologically in only less than half the cases. Endometrial carcinoma was suspected on hysteroscopic view in two cases of a total of seven proven cases. In three cases initially an endometrial polyp and in two cases a fibroid was diagnosed. Once the diagnosis was missed even after biopsy taking. CONCLUSIONS: Diagnostic hysteroscopy is a valuable diagnostic tool in diagnosing structural intra-cavital pathology, very suitable for the outpatient clinic. The value in diagnosing hyperplasia or endometrial carcinoma is limited and even after guided biopsy a malignancy cannot be ruled out.

Biopsy↗
PubMed2003

Histologic features of reflux-attributed laryngeal lesions.

The purpose of this study was to compare the histologic appearance of the normal larynx and the larynx presumably affected by reflux. A secondary objective was to determine the safety of performing laryngeal biopsies. Biopsy specimens from the interarytenoid area of 15 patients with reflux laryngitis were compared with specimens from 9 control subjects. Control subjects were asymptomatic, had normal 24-hour pH studies, and had a normal videostroboscopic laryngeal examination. Patients with reflux laryngitis had abnormal pH studies and videostroboscopic examinations. There were no consistent changes in mucosal detail or cellular infiltration that distinguished the biopsies from normal patients and those with reflux laryngitis. In this small sample of subjects it was not possible to define any characteristic histologic features of reflux laryngitis.

Biopsy↗