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PubMed · 12424065

Genetic testing for melanoma.

Richard Kefford·Julia Newton Bishop·Margaret Tucker·Brigitte Bressac-de Paillerets·Giovanna Bianchi-Scarrá·Wilma Bergman·Alisa Goldstein·Susana Puig·Rona Mackie·David Elder·Johan Hansson·Nicholas Hayward·David Hogg·Håkan Olsson·Melanoma Genetics Consortium
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Cyclin-Dependent Kinase 4Cyclin-Dependent KinasesGenes, p16Genetic Predisposition to DiseaseGenetic TestingGerm-Line MutationHumansMass ScreeningMelanomaPedigreeProto-Oncogene ProteinsRisk FactorsJournal ArticleResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, P.H.S.

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Richard Kefford, Julia Newton Bishop, Margaret Tucker, Brigitte Bressac-de Paillerets, Giovanna Bianchi-Scarrá, Wilma Bergman, Alisa Goldstein, Susana Puig, Rona Mackie, David Elder, Johan Hansson, Nicholas Hayward, David Hogg, Håkan Olsson, Melanoma Genetics Consortium. 2002. Genetic testing for melanoma.. https://doi.org/10.1016/s1470-2045(02)00894-x

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A simple and efficient synthesis of 2-amino pyrido[2,3-d]pyrimidine derivatives was accomplished via a three-component reaction under microwave irradiation without catalyst. This method had many dramatic advantages such as the short reaction time, high yield, and broad substrate scope, as well as convenient operation. We provide new series of potential biologically active compounds as inhibitors of Cdk4.

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