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PubMed · 12471808

[Target and therapeutic microbubbles].

J L Vanoverschelde
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Abstract

Because ultrasound microbubbles lower the threshold for cavitation by ultrasound energy, they may be used as cavitation nuclei for drug and gene delivery. By tailoring the physical properties of microbubbles and coating materials, drugs and genetic drugs can be incorporated into ultrasound contrast agents. As the microbubbles enter the region of insonation, the microbubbles cavitate, locally releasing the therapeutic agents.

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AnimalsContrast MediaDrug Delivery SystemsEchocardiographyEthanolFibrinolytic AgentsGenetic TherapyHumansRabbitsRatsUltrasonicsEnglish AbstractJournal Article

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J L Vanoverschelde. 2002. [Target and therapeutic microbubbles].. https://doi.org/10.1016/s0003-3928(02)00114-2

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