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PubMed · 12474485

Onchocerciasis-associated morbidity: hypothesis.

Anthony R Mawson·Musau WaKabongo
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Abstract

Tissue concentrations of vitamin A in Onchocerca volvulus are about 8 times higher than those of the host. About 100,000 microfilariae (mf) die every day in heavily infected persons. Onchocerciasis-associated morbidity may be due in part to the release of retinoids from dying mf and their gradual accumulation to toxic concentrations in affected tissues.

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AnimalsAnthelminticsHumansIvermectinOnchocerca volvulusOnchocerciasisVitamin AJournal Article

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Anthony R Mawson, Musau WaKabongo. Onchocerciasis-associated morbidity: hypothesis.. https://doi.org/10.1016/s0035-9203(02)90434-7

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