PubMed Health⌕ Search

PubMed · 12474610

Functional imaging in stroke.

Abstract

Recent advances in magnetic resonance techniques make it possible to image physiological parameters such as molecular diffusion, tissue perfusion and cortical activation. These techniques greatly contribute to the early detection and to the understanding of the pathophysiological evolution and recovery from ischaemic stroke.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

H R Jäger, N S Ward. 2002. Functional imaging in stroke.. https://doi.org/10.12968/hosp.2002.63.11.1911

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

Targeted prefrontal cortical activation with bifrontal ECT.

The anatomical brain regions involved in the therapeutic and adverse actions of electroconvulsive therapy (ECT) are unknown. Previous studies suggest that bifrontal vs. bitemporal ECT differ in therapeutic efficacy and cognitive side effects. We therefore performed cerebral blood flow (CBF) imaging during bitemporal vs. bifrontal ECT-induced seizures to identify regions crucial for the differences between these treatments. Patients with major depression, undergoing bitemporal or bifrontal ECT, were studied. Ictal-interictal SPECT images were analyzed with statistical parametric mapping for bitemporal (n=11 image pairs in 8 patients) and bifrontal (n=4 image pairs in 2 patients) ECT-induced seizures to identify regions of ictal CBF changes. Bifrontal ECT was found to cause increases in CBF in prefrontal and anterior cingulate regions. Bitemporal ECT, however, caused CBF increases in the lateral frontal cortex and in the anterior temporal lobes. In bifrontal ECT, a greater increase in prefrontal activation, while sparing the temporal lobes, may result in a better therapeutic response and fewer adverse effects on memory than bitemporal ECT.

Cerebrovascular Circulation↗