Selective functionalization of small organic molecules using electrophilic nitrogen sources.

Iain D G Watson; Andrei K Yudin

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PubMed · 12478721

Selective functionalization of small organic molecules using electrophilic nitrogen sources.

Iain D G Watson·Andrei K Yudin

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Abstract

Selective functionalization of small organic molecules using electrophilic nitrogen-containing reagents has been a long-standing challenge in organic synthesis. The delivery of nitrogen in the corresponding reactions can occur via a nitrenoid, radical or electrophilic pathway. Nitrogen transfer processes result in the rapid synthesis of diverse and useful products, such as aziridines, aminohalides, aminoalcohols, sulfimines and amines. This review outlines advances in the field during the past two years.

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Animals Humans Nitrogen Pharmaceutical Preparations Technology, Pharmaceutical Journal Article Research Support, Non-U.S. Gov't Review

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Iain D G Watson, Andrei K Yudin. 2002. Selective functionalization of small organic molecules using electrophilic nitrogen sources.. https://pubmed.ncbi.nlm.nih.gov/12478721/

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