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Micellar electrokinetic chromatography: current developments and future.

Manuel Molina·Manuel Silva
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Abstract

This review highlights recent methodological and instrumental advances in micellar electrokinetic chromatography (MEKC). Enhancements in sensitivity and selectivity of the technique through the use of on-line preconcentration approaches (stacking and sweeping) and nonconventional pseudostationary phases, namely nonionic and zwitterionic surfactants, mixed micelles and polymers, are discussed in detail. Laser-induced fluorescence and mass spectrometry, as alternatives to UV-absorption detection, have been covered to evaluate their advantages and limitations when applied to analysis in an MEKC format. Some thoughts on future directions in this area such as in-capillary reactions, coated capillaries and MEKC on microchips are also presented.

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Chromatography, Micellar Electrokinetic CapillaryEquipment DesignLasersMass SpectrometrySurface-Active AgentsJournal ArticleResearch Support, Non-U.S. Gov'tReview

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Manuel Molina, Manuel Silva. 2002. Micellar electrokinetic chromatography: current developments and future.. https://doi.org/10.1002/elps.200290009

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