New microinsemination techniques for laboratory animals.

A Ogura; N Ogonuki; K Inoue; K Mochida

doi:10.1016/s0093-691x(02)01276-1

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PubMed · 12499020

New microinsemination techniques for laboratory animals.

A Ogura·N Ogonuki·K Inoue·K Mochida

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Abstract

Since the development of a reliable mouse intracytoplasmic sperm injection (ICSI) technique in 1995, microinsemination techniques have been widely applied in several laboratory species. As gametes and embryos have specific biological and biochemical features according to the species, technical improvements are necessary for successful microinsemination that subsequently leads to normal fetal development in several species. Recent advanced reproductive research involving genetic engineering often depends on microinsemination techniques that require a high degree of skill, and new human assisted reproductive technology (ART) requires experimental models using laboratory animals. The accumulation of technical improvements in these fields should accelerate the development of microinsemination techniques in mammals, including humans.

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Animals Animals, Laboratory Female Genetic Therapy Humans Infertility, Male Insemination, Artificial Male Pregnancy Reproductive Techniques, Assisted Seminiferous Tubules Spermatogenesis Spermatogonia Spermatozoa Stem Cells Journal Article Review

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A Ogura, N Ogonuki, K Inoue, K Mochida. 2003-01-01. New microinsemination techniques for laboratory animals.. https://doi.org/10.1016/s0093-691x(02)01276-1

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