Architectural changes in the developing human brain based on the matrix cell theory.

Yasuhiro Nakamura

doi:10.1111/j.1741-4520.2002.tb00889.x

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Architectural changes in the developing human brain based on the matrix cell theory.

Yasuhiro Nakamura

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Abstract

Architectural changes in the developing human brain are discussed based on the matrix cell theory. Neural stem cells/matrix cells with self-renewing ability and multipotency exist in the developing human brain in vivo. The brain development is divided into three stages and the cell differentiation is time regulated. Immunohistochemical distribution of various markers for brain development is summarized and categorized along with differentiation lineages. Particularly, the existence of glial fibrillary acidic protein is re-evaluated in the developing human brain. The commonly used terms and concepts "radial glial fiber" or "subventricular zone" are also re-evaluated.

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Biomarkers Brain Humans Immunohistochemistry Mitosis Stem Cells Journal Article Research Support, Non-U.S. Gov't Review

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Yasuhiro Nakamura. 2002. Architectural changes in the developing human brain based on the matrix cell theory.. https://doi.org/10.1111/j.1741-4520.2002.tb00889.x

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