ECVAM's activities on computer modelling and integrated testing.

Andrew P Worth

doi:10.1177/026119290203002s22

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ECVAM's activities on computer modelling and integrated testing.

Andrew P Worth

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Abstract

This paper introduces the basic concepts of quantitative structure-activity relationship (QSAR), expert system and integrated testing strategy, and explains how the analogy between QSARs and prediction models leads naturally to criteria for the validation of QSARs. ECVAM's in-house research programme on QSAR modelling and integrated testing is summarised, along with plans for the validation of QSAR models and expert system rulebases at the European Union level.

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Animal Testing Alternatives Animals Computer Simulation European Union Expert Systems Humans Predictive Value of Tests Quantitative Structure-Activity Relationship Reproducibility of Results Toxicity Tests Xenobiotics Journal Article Review

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Andrew P Worth. 2002. ECVAM's activities on computer modelling and integrated testing.. https://doi.org/10.1177/026119290203002s22

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