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PubMed · 1251688

Decrease in the mortality rates for low-birth-weight infants after phenobarbitone treatment.

D Trolle
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Abstract

A daily dosage of 100 mg phenobarbitone administered orally to pregnant women for three days or more immediately before delivery has reduced the various mortality rates for low-birth-weight infants by 50% or more. Since it is hardly possible to treat all pregnant women in this way it is recommended to administer phenobarbitone to women with high-risk pregnancies such as former stillborn infant, former premature delivery, pregnancy complications, and planned induction of premature labour before the 37th week and until delivery takes place. If the mothers of low-birth-weight infants have not been adequately treated it is recommended that the newborn infant be given phenobarbitone injections immediately after birth and at 8-hour intervals, 10 injections in all.

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Birth WeightFemaleFetal DeathHumansInfant MortalityInfant, NewbornInfant, PrematurePhenobarbitalPregnancyPregnancy ComplicationsJournal Article

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BibTeXRIS

D Trolle. 1976. Decrease in the mortality rates for low-birth-weight infants after phenobarbitone treatment.. https://doi.org/10.3109/00016347609156777

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Prediction of light-for-gestational age at delivery in twin pregnancies: an evaluation of fetal weight deviation and growth discordance measured by ultrasound.

The purpose of this retrospective study was to evaluate and discuss different ultrasound methods widely used, among other things, as predictors for light-for-gestational age (LGA) in twin pregnancies. The methods evaluated and compared as predictors for LGA at birth were: (1) Difference between twins in biparietal diameter; (2) difference in abdominal diameter; (3) the percentage difference in estimated fetal weight between twins; and (4) estimation of the weight deviation from the expected weight during pregnancy. The study comprised 66 twin pregnancies, examined by ultrasound scanning less than 15 days before delivery. Using Relative Operating Characteristic curves (ROC curves) estimated fetal weight deviation was the most sensitive and specific of the methods. It is stressed that fetal discordance is not the appropriate predictor of LGA at birth in twin pregnancies.

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