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PubMed · 12524644

Chemoembolization for hepatic metastases.

Michael Gee·Michael C Soulen
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Abstract

Liver metastases are one of the most difficult therapeutic challenges in modern oncologic practice. Few systemic therapies are effective for solid tumors in the liver. Resection is possible in a minority of patients and usually not curative. Image-guided therapies such as chemoembolization offer substantial intensification of treatment by combining tumor ischemia, increased drug concentrations, prolonged dwell time, and reduced systemic toxicity. Although not a curative therapy, durable responses are seen in most adenocarcinomas, which may contribute to prolongation and preservation of quality of life by delaying liver failure in patients with liver-dominant disease.

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AdenocarcinomaAntineoplastic Combined Chemotherapy ProtocolsCarcinoma, NeuroendocrineChemoembolization, TherapeuticColorectal NeoplasmsEye NeoplasmsHepatic ArteryHumansInfusions, Intra-ArterialLiver NeoplasmsMelanomaPatient SelectionRadiography, InterventionalTomography, X-Ray ComputedJournal ArticleReview

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Michael Gee, Michael C Soulen. 2002. Chemoembolization for hepatic metastases.. https://doi.org/10.1053/tvir.2002.36422

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