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PubMed · 12542444

A new platelet parameter, the mean platelet component, can demonstrate abnormal platelet function and structure in myelodysplasia.

D R Brummitt·H F Barker·N Pujol-Moix
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Abstract

The mean platelet component (MPC) is a new platelet parameter generated by the Bayer ADVIA 120 full blood count analyser as part of the routine complete blood count (CBC) test cycle. We report a case of myelodysplasia with bleeding complications and abnormal template bleeding time in whom low mean platelet component parameters were associated with partial platelet granule deficiency, demonstrated by transmission electron microscopy. We suggest that the mean platelet component is an inexpensive and rapid test to screen for platelet dysfunction related to ultrastructural abnormalities in myelodysplasia.

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Blood Platelet DisordersBlood PlateletsFemaleHemorrhageHumansMicroscopy, ElectronMiddle AgedMyelodysplastic SyndromesPlatelet Function TestsCase ReportsJournal Article

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D R Brummitt, H F Barker, N Pujol-Moix. 2003. A new platelet parameter, the mean platelet component, can demonstrate abnormal platelet function and structure in myelodysplasia.. https://doi.org/10.1046/j.1365-2257.2003.00488.x

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