PubMed · 12545775
[Calcium dependent synaptic plasticity].
Abstract
Recent work shows that the intracellular free Ca2+ concentrations ([Ca2+]i) of the presynaptic and postsynaptic neurons play crucial signaling roles in short- and long-term synaptic plasticity. Residual [Ca2+]i followed conditioning stimulation may cause short-term synaptic enhancement. Presynaptic [Ca2+]i could influence the replacing of presynaptic depressed vesicles, as well as encode the precise relative timing of presynaptic input and postsynaptic activity and generate long-term synaptic modification of opposite polarity(LTP or LTD).
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Y Dou, J Yan, Y Y Wu, R Y Cui, C L Lu. 2001. [Calcium dependent synaptic plasticity].. https://pubmed.ncbi.nlm.nih.gov/12545775/
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