Emerging high-throughput drug target validation technologies.

Leodevico L Ilag; Jocelyn H Ng; Gerald Beste; Stefan W Henning

doi:10.1016/s1359-6446(02)02429-7

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Emerging high-throughput drug target validation technologies.

Leodevico L Ilag·Jocelyn H Ng·Gerald Beste·Stefan W Henning

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Abstract

Identifying the right target for drug development is a critical bottleneck in the pharmaceutical and biotech industries. The genomics revolution has shifted the problem from a scarcity of targets to a surplus of putative drug targets. As the validity of a target cannot be simply inferred from correlative data, the key is confirmation of the causative role of a gene product in a particular disease. It should therefore be recognized that an effective therapeutic strategy requires an appropriate target validation technology to verify the right target.

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Leodevico L Ilag, Jocelyn H Ng, Gerald Beste, Stefan W Henning. 2002-09-15. Emerging high-throughput drug target validation technologies.. https://doi.org/10.1016/s1359-6446(02)02429-7

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