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PubMed · 12553903

Sensing stretch is fundamental.

Neal D Epstein·Julien S Davis
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Abstract

Stretch induces changes in cardiomyocyte biology that are implicated in heart failure, but the mechanism by which stretch is sensed and signals are transduced is unknown. New understanding of the Z disc elements of contractile units are beginning to elucidate the mechanism of stretch sensing and its relation to cardiac adaptation and disease.

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AnimalsBiophysical PhenomenaBiophysicsContractile ProteinsFeedbackHeart FailureHumansMyocardial ContractionMyocardiumMyofibrilsJournal ArticleReview

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Neal D Epstein, Julien S Davis. 2003-01-24. Sensing stretch is fundamental.. https://doi.org/10.1016/s0092-8674(03)00037-0

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