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Interferon beta-1a in primary progressive multiple sclerosis.

Siobhan M Leary·Alan J Thompson
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Abstract

There is currently no disease-modifying treatment proven to be of efficacy in primary progressive multiple sclerosis (PPMS). However, a number of therapeutic trials have recently been specifically designed for this group. These include a randomised controlled trial of interferon beta-1a which is discussed here. It is hoped that therapeutics in primary progressive multiple sclerosis will continue to expand and effective therapeutic agents will be developed.

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Adjuvants, ImmunologicAdolescentAdultAntineoplastic AgentsDisability EvaluationDisease ProgressionDose-Response Relationship, DrugFollow-Up StudiesGlatiramer AcetateHumansInterferon beta-1aInterferon beta-1bInterferon-betaMagnetic Resonance ImagingMiddle AgedMitoxantroneMultiple Sclerosis, Chronic ProgressiveNeuroprotective AgentsPeptidesRiluzoleTreatment OutcomeClinical TrialClinical Trial, Phase IIIJournal ArticleRandomized Controlled Trial

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Siobhan M Leary, Alan J Thompson. 2003-02-15. Interferon beta-1a in primary progressive multiple sclerosis.. https://doi.org/10.1016/s0022-510x(02)00350-7

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